OrganOx Secures $142M to Revolutionize Liver Transplantation with the OrganOx metra®

OrganOx, the innovator behind the cutting-edge OrganOx metra®, is thrilled to announce a significant funding milestone of $142,000,000. As a company dedicated to "Living Organs For Life," OrganOx is transforming the landscape of transplantation with its transportable, automated ex vivo liver perfusion device. This groundbreaking technology, developed over more than 15 years by founders Professor Peter Friend and Professor Constantin Coussios, has revolutionized conventional organ preservation methods. Traditionally, livers were stored at 4˚C using non-physiological solutions that primarily aimed to slow decay. In stark contrast, the OrganOx metra® leverages warm preservation techniques that mimic the human body’s environment, continuously perfusing the liver with oxygen-carrying red cells at 37˚C while providing essential nutrients. This innovative method not only keeps the organ functional—allowing it to produce bile, metabolize glucose, and maintain a balanced pH—but also extends preservation times and facilitates objective assessment of organ health prior to transplant. As a University of Oxford spin-out established in April 2008, OrganOx has always been at the forefront of advancing transplantation science. This latest funding round will enable the company to accelerate the adoption and further development of its ex vivo liver perfusion technology, broaden its research efforts, and expand its market reach. By providing a platform to save more lives with organs that might otherwise be discarded, OrganOx’s mission is clear: to enhance organ viability, increase transplant success rates, and ultimately transform patient outcomes. This investment marks a new chapter in the pursuit of more effective and reliable transplantation treatments, positioning OrganOx as a leader in the next wave of medical innovation.