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Harrow Acquires Melt Pharmaceuticals for Non-Opioid Sedation Medicines

Melt Pharmaceuticals acquired by Harrow

Acquisition

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Acquired

Melt Pharmaceuticals

Pharmaceutical Manufacturing

Undisclosed amount

September 26, 2025

Harrow logo
Acquirer

Harrow

Harrow has acquired Melt Pharmaceuticals, Inc. for an undisclosed amount. This corporate acquisition sees Harrow integrate Melt Pharmaceuticals, a clinical-stage pharmaceutical company focused on developing and commercializing patented non-intravenous and non-opioid sedation and analgesia medicines. The transaction is aimed at expanding Harrow's therapeutic offerings and market presence within the medical procedures sector.

Melt Pharmaceuticals' core business centers on its innovative approach to procedural sedation. The company develops non-opioid drug formulations designed for short-duration medical procedures conducted in outpatient and in-office settings. Its technology aims to provide needle- and opioid-free options that may replace or supplement existing sedation modalities, addressing a significant market of over 100 million medical procedures annually in the United States. Melt's focus is on improving the patient experience by offering alternatives to traditional intravenous and opioid-based methods.

This strategic acquisition is expected to significantly enhance Harrow's portfolio by integrating Melt's unique drug candidates. For Harrow, the deal represents an opportunity to enter or strengthen its position in the rapidly evolving market for non-opioid pain and sedation management. Melt Pharmaceuticals' pipeline, particularly its combination non-opioid drug formulations, aligns with a broader industry shift towards safer, more convenient, and less invasive procedural care, making it a compelling addition for a company like Harrow.

The synergy between the two companies is anticipated through the combination of Melt’s specialized clinical development expertise and Harrow’s resources and potential commercialization capabilities. The integration of Melt's patented technology into Harrow's operational framework could accelerate the development and market penetration of these non-intravenous, non-opioid solutions. Looking forward, the combined entity aims to capitalize on the substantial demand for advanced, patient-friendly sedation and analgesia options, potentially transforming care for millions undergoing routine medical procedures.

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